Tissue microarray- A review

Cancer is a highly variable disease with multiple heterogeneous genetic and epigenetic changes. Functional studies are essential to understand the complexity and polymorphisms of cancer. Tissue microarray (TMAs) is a powerful new technology designed to assess the expansion of proteins or genes across large sets of tissue specimens assembled on a single glass microscope slide, efficiently and economically. In this review, we are highlighting the different aspects of technology such as contribution of TMA, advantages, disadvantages and utilization of technique in the diagnosis of oral cancer.