Oral prophylaxis as an adjunct to systemic H.pylori eradication therapy

Introduction: Helicobacter pylori is the known bacteria, causing multiple gastric disorders. Its prevalence in dental plaque noted by multiple researchers. The presence of helicobacter pylori in dental plaque even after systemic eradication done using triple drug therapy noted by few. Purpose of this study was to establish need of oral prophylaxis as an adjunct to systemic eradication of H.pylori. Materials and Methods: Total of 22 H.pylori positive patients divided in two groups irrespective of gender. 14 patient underwent oral prophylaxis and remaining 8 subjects did not, along with triple drug therapy for systemic eradication of H.pylori. Plaque samples from only posteroior teeth collected and PCR was done for detection of H.pylori strains after 6 months. Results: Statistical significant reduction in prevalence of H.pylori noted in patients undergone oral prophylaxis along with anti-H pylori therapy. Conclusion: Oral prophylaxis has to be considered along with anti-H pylori eradication therapy to prevent dental plaque acting as a reservoir causing reinfection.