Establishment of reference range for thyroid hormones (T3, T4 & TSH) in adult female population at clinical biochemistry laboratory of GCS medical college & hospital- A descriptive study

Aim: To establish reference range of T3, T4 and TSH of adult female population at Clinical Biochemistry Laboratory GCS Hospital, Ahmedabad. Materials and Methods: The study was conducted among 151 healthy females who had undergone health check up at GCS hospital. Blood samples were collected for a period from June, 2015 to October, 2016. The mean age of all the females was 42.49 and the median was 42.00 years, with ages ranging from 23 to 70 years. Participants who had diabetes, hypertension, history of drug intake or any other systemic disease were not included in the study. Results: Established reference ranges are 0.77-1.69 ng/ml, 5.37-12.10 µg/dl and 0.50-5.06 µIU/ml for T3, T4 and TSH hormones respectively. Conclusion: The thyroid hormone reference interval of the study considerably varies from that of manufacturer's range. There should be need for population based specific range for clinical laboratories running at tertiary hospitals.