A study on serum magnesium correlation with metabolic syndrome in a rural tertiary care hospital in Kanchipuram District, Tamil Nadu

Introduction: Magnesium which is present in the extra-cellular compartment is very vital for antagonising calcium physiology. Hypomagnesemia is sensed as a stressor by our body suggesting that magnesium metabolism plays an essential role in the evolving of metabolic syndrome. Statistical data on the association of hypomagnesemia with metabolic syndrome would help the clinicians to overcome therapeutic compliance of the patients, so our study was designed to estimate the levels of serum magnesium in patients with metabolic syndrome and healthy controls and to correlate it with the components of metabolic syndrome. Materials and Methods: The present case-control study was conducted in patients with metabolic syndrome attending a tertiary care hospital in Kanchipuram District during the period from April to December 2017. 65 patients of metabolic syndrome & 65 controls who attended the various out-patient departments of the hospital were selected for the study. Waist circumference, blood pressure, fasting plasma glucose, serum triglycerides, HDL-cholesterol and serum magnesium was estimated, compared and analyzed. Results: This study has proven that the mean serum magnesium level in patients with metabolic syndrome was 1.3±0.07mg/dL while in controls it was 2.06±0.26mg/dL. A highly significant difference (p <0> Conclusion: The study has made the association of hypomagnesemia and metabolic syndrome evident. Further studies with larger sample size will help in providing data to implement supplementation of oral magnesium for effective correction of metabolic derangements observed in metabolic syndrome.