Malignant peripheral nerve sheath tumor (Schwannoma) of the dorsal penis: A case report and review of the literature

Malignant peripheral nerve sheath tumors (MPNST) are rare, aggressive soft tissue sarcomas arising from peripheral nerves that present great challenges to known treatment modalities. Here, we present a case of MPNST involving the dorsum of a penis in a 13-month-old boy. The mass was incomplete excised and a circumcision was performed. Histological study revealed spindle cell tumor of the lesion. Immunohistochemistry showed a strong positive staining for tumor cells. A high grade malignant peripheral nerve sheath tumor was diagnosed.