Clinico-histomorphological spectrum of abnormal uterine bleeding

Introduction: Abnormal uterine bleeding is considered as one of the most common and perplexing problems both to the patient and gynecologist. Histopathological diagnosis of organic cause of menorrhagia plays an important for appropriate and accurate therapy. Aims and Objectives: The present study mainly aimed at correlating histopathological findings with age, parity and bleeding pattern presented by the patient and to study various associated organic lesions in abnormal uterine bleeding. Materials and Methods: A reterospective study of 111 hysterectomies in patients with complaints of abnormal uterine bleeding over a period of one year from June 2016-May 2017. The histopathological findings with clinical data that includes age, parity, presenting symptoms and other details of the patients with abnormal uterine bleeding was collected and analyzed. Results: In this study, majority of cases were in 4th & 5th decade (81.08%) and were multiparous (93.7%). Menorrhagia was the most frequent presenting complaint (58.57%) followed by metrorrhagia in 13.51%. Of the 111 cases, 51.35% of cases showed histological features of dysfunctional uterine bleeding followed by 48.65% cases with organic lesions. Among organic lesions maximum number of cases of adenomyosis followed by leiomyoma was observed. Conclusion: Clinico-histomorphological evaluation of abnormal uterine bleeding in our study showed maximum number of dysfunctional uterine bleeding followed by adenomyosis and leiyomyoma. Age has definite influence on endometrial histology. There is no constant relationship between the pattern of endometrium and the type of bleeding in cases of abnormal uterine bleeding.