Assessment of clinicopathologic features of patients with cutaneous leishmaniasis: A tertiary care centre study

Introduction: Cutaneous Leishmaniasis (CL) is a widespread parasitic skin pathology happening due to Leishmania tropica and Leishmania minor. Hence; we planned the present study to assess the clinic-pathologic features of patients with CL. Materials and Methods: We planned the current investigation to clinic-pathologic assess cutaneous Leishmaniasis cases affecting a known population. 35 cases of cutaneous Leishmaniasis were included in the present study. Detailed demographic and clinical data of all the subjects was summarized. Clinical examination was thoroughly done in all the subjects. 5 ?m sections were obtained and were stained with H and E stain and Giemsa stain. All the sections were evaluated by experienced Pathologists. Analysis of all the results was done by SPSS software. Results: In the present study, we observed that hyperkeratosis was the predominant epidermal finding found to be present in 22 patients, followed by parakeratosis and acanthosis. Common dermal findings found in the present study were granuloma formation, lymphocyte aggregation and necrosis. Plasma cells and eosinophil leukocytes were also seen. Conclusion: CL represents a broad spectrum of clinic-pathologic variety, and it might mimic other inflammatory pathologies.