Ban of Fixed Dose Combination on India Impact and Implications

Fixed dose combinations FDCs of drugs are important for public health perspective and commonly used for the treatment of pain and inflammation, hypertension, diabetes, malaria, tuberculosis, HIV AIDs etc. These ailments are considered to be the foremost threats to health in the world today. FDCs have proved to be advantageous as they are safe and effective. They increase efficiency, reduce the incidence of adverse drug effects, and improve patient compliance. The FDCs offer low cost as compared to individual components of active ingredients. On other hand if administered in unprofessional way, FDCs have given problem of drug resistance in the case of antimicrobial treatment especially in case of treatment of tuberculosis malaria. In some instances wrong understanding of FDCs have been proved to be fatal. 1 The FDCs being extensively used for so long for various ailments in order to get combination of drugs for a particular disease at low cost. Doctors appreciated the use of FDCs in their practice. Then problems started arising about the irrational use and safety profile of these drug combinations, which makes regulatory bodies to take action against the use of FDCs. Petitions being filed in supreme court against the ban imposed on FDCs by regulatory bodies by the pharma companies. At the end 15 FDCs were spared to be banned and rest 328 FDCs were banned to be manufactured, market and sale.The article aims at identifying the reasons behind banning the fixed dose combinations and the impact of the ban on pharma market. Aprajita Rastogi | Prof. Ramesh K Goyal "Ban of Fixed Dose Combination on India: Impact and Implications" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-5 , August 2019, URL: https://www.ijtsrd.com/papers/ijtsrd25313.pdfPaper URL: https://www.ijtsrd.com/pharmacy/other/25313/ban-of-fixed-dose-combination-on-india-impact-and-implications/aprajita-rastogi