A Critical Analysis of HPV Vaccination in Children | Biomedgrid

Worldwide, infection with HPV viruses is the most common sexually transmitted disease. The prevalence of HPV infection varies considerably from country to country and can change significantly with changes in lifestyle and sexual behavior. Every year, about half a million women worldwide develop cervical cancer, with up to four-fifths of them from developing countries. The lack or underutilization of cancer screening programmers in developing countries plays a decisive role in this. It is estimated that around 230,000 women worldwide die of cervical cancer every year [1]. In Central Europe, cervical cancer is the eleventh most common cancer among women of all age groups. It is the second most common malignant tumor in women under 45 years of age, but accounts for only 3.2% of all cancers and 1.8% of all cancer deaths in women. A multifactorial cause is propagated, whereby primarily proteins and genome parts of different HPV viruses but also other cofactors such as a young age in initial diagnosis, immunosuppression, smoking and co-infections with herpes simplex virus and infections with chlamydia play a not insignificant role. The long latency between HPV primary infection and cancer suggests that the other factors such as sexual behavior, genetic predisposition, nutritional status and social educational status may have an influence.