Introduction to nanoMIPS Prepared by Solid-Phase approach as an Alternative for Antibodies in the pseudo-ELISA Diagnostic Assay | Biomedgrid

The presented article describes the possibilities of replacing antibodies with artificial molecules in the pseudo-ELISA diagnostic assay. The enzyme-linked immunosorbent assay ELISA is based on specific antibodies, linked to an enzyme, to detect the determined molecule. However, the production of antibodies is complicated and therefore its price is high. Also, the stability of the antibodies is inadequate for their price. For this reason, research into artificial molecules that could replace natural immunoglobulins is becoming extremely important. The article presents studies comparing the use of antibodies and molecularly imprinted nano molecules, nanoMIPs, as artificial antibodies in the ELISA assay.