STUDY ON PRESCRIPTION PATTERN OF ANTI HYPERTENSIVES IN PATIENTS OF PREGNANCY INDUCED HYPERTENSION AT TERTIARY CARE HOSPITAL

Introduction:During pregnancy, Hypertension has become the most common medical problem and it is also remains main cause of maternal and fetal morbidity and mortality. It complicates almost 10% of all pregnancies. Aim:Present study was conducted to evaluate the prescribing pattern in pregnancy induced hypertension. Methods:A cross sectional study was carried out by evaluating prescription of 110 pregnant womens, who had diagnosed with PIH in Department of Pharmacology in collaboration with Department of Gynecology and Obstetrics. The data was analyzed by using SPSS software and results were expressed in percentage. Results:A Total of 110 Prescriptions were collected, among them, 56% of womens were diagnosed with stage-II hypertension (B.P≥160/≥100) and rest were diagnosed stage-I. In this, 77.2% of cases had received a single antihypertensive drug, while 18.1% had received two antihypertensive drugs& 4.5% received triple drugs therapy. Methyldopa was given in 35 patients (i.e. 31.8%. cases) as monotherapy and followed by Labetalol in 27 patients (24.5 %.cases). Combination of methyldopa and labetalol was the most common dual antihypertensive regimen given in 11.8 % of cases. Conclusion: During treatment with antihypertensive agents, prescriber should be very cautious as they are having history of causing foetal abnormality. Our study concluded that incidence of PIH is high and Methyldopa was the commonest drug given either alone or in combination therapy, as it is a safest during pregnancy. Patients also received other drugs for various purposes like, calcium supplements, iron, folic acid and multivitamin