DRESS INDUCED BY DAPSONE : A RARE LIFE - THREATENING COMPLICATION OF DAPSONE TREATMENT
Journal: International Journal of Advanced Research (Vol.7, No. 9)Publication Date: 2019-09-02
Authors : Zineb Rachadi OuafaHocar; Said Amal.;
Page : 238-241
Keywords : Dapsone; DRESS syndrome; HLA-B*13 : 01; HHV6; eosinophilia.;
Abstract
Dapsone is widely used for a variety of infectious, immune and hypersensitivity disorders. However, the use of dapsone may be associated with a plethora of adverse effects, whose DRESS syndrome potentially deadly. We report the clinical case of a 22 years old woman who was treated by Disulone ? 100mg/day for lichen pigmentosus. 3 weeks later, she presented a DRESS syndrome with Dapsone, successfully managed by oral steroids. The aim of this work was to highlight the main features of DRESS syndrome with Dapsone, through a systematic review of cases published in the medical literature, to enable rapid diagnosis and appropriate management of this syndrome
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