Nicotine is Insufficient as a Carcinogen, It’s Functions as a Tumor Promoter on Purpose | Biomedgrid

Nicotine constitutes approximately 0.6~3.0% of the dry weight of tobacco. Like anything that enters the body, nicotine is also metabolized. Therefore, any activity that increases your metabolic rate can help speed up the clearance of nicotine. Nicotine also promotes cancer growth, angiogenesis, and neovascularization. Thereby, nicotine impeding apoptosis, promoting tumor growth and activating growth factors. This article provides a brief description of nicotine is unusual in comparison to most drugs, as its concentration profile changes from induced tumor growth to cytotoxic with increasing doses. The concentration of nicotine stimulated cell growth correspond to low concentration was needed, while high concentration was cytotoxic