Rhabdomyolysis After Cocaine Consumption-Case Report | Biomedgrid

Objective: Rhabdomyolysis, a potentially fatal syndrome, is characterized by degradation of muscular skeletal tissue trigger fatal complications such as acute renal failure. Methods: Clinical evaluation and biochemical measurements were performed on a Brazilian soldier after he was admitted at the emergency department of the Military Hospital of Manaus in August 2014. A 23-year-old soldier reported having consumed about six grams of cocaine. Results: Clinical laboratory measurement of serum showed a significant increase in the levels of indirect markers of muscle lysis. Serum creatine kinase fraction MM (CK) level increased up to 99.500 U/L and creatine kinase MB fraction (CK-MB) up to 6.500U/L. Changes in electrolytes also increased (sodium=1.730mmol/L, potassium=42.1mmol/L, phosphorus =48.3mg/dl, chlorine =1.243mmol/L and magnesium=36.1mg/dl). Changes in kidney functions also occurred (urea =302.6mg/dl and creatinine=11.1mg/dL). The levels of albumin (33.4g/dl) and lactate dehydrogenase LDH (22,545U/L) also increased. Further, qualitative tests for troponin and myoglobin were positive. Intervention: The soldier stayed in the intensive care unit (ICU) for five days.