New Analytical Method Development for the Active Pharmaceutical Ingredients Using Visible SpectrophotometryJournal: International Journal of General Medicine and Pharmacy (IJGMP) (Vol.2, No. 2)
Publication Date: 2013-05-31
Authors : Chandrashekara K N; Srinivas K;
Page : 55-64
Keywords : Spectrophotometry; Quantitative Analysis; Pharmaceutical Analysis;
Method-A, depends on the oxidation of Teicoplanin with ferric chloride and 1,10-phenanthroline to form a blood red colored chromogen. The Method B is based on reaction of Teicoplanin with ferric chloride 2,2? bipyridyl to form blood colored chromogen. Method C is based on the reduction of Ferric ions of the reagent Ferric chloride to Ferrous ions by the drug. The Method A is based on the formation of golden yellow colored chromogen, due to ion-association of Tenofovir with Metanil Yellow dye in Chlolorform. Method B is based on the formation of golden yellow colored chromgen due to ion-association of Tenofovir with Solochrome Black dye in Chlolorform,. The Method C is based on the formation of blood red colored chromogen with Ferric Chloride and 2,2-Bipyridyl . Methods (A, B and C) and Methods (A, B and C) have been developed for the estimation of Tenofovir Disoproxil Fumerate and Emtricitabine in its pharmaceutical dosage form.
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Last modified: 2013-04-13 19:46:52