Triterpenoids of Nerium oleander shows Antifertility effect in Male Albino Rats

Antifertility activity of methanolic extract of the stem of Nerium oleander was carried out on male albino rat. After the careful experiments, the results revealed that oral administration of methanolic extract of the stem of Nerium oleander affected male fertility by two means, antispermatogenic and antiandrogenic action. It might be due to the presence of some triterpenoids compounds. So it could be a scope of developing an ideal male contraceptive, due to its antispermatogenic effects.