Clinical, Hormonal and Metabolic Characterization of Mexican Women who had Gestational Diabetes in the Institute of Security and Social Services of workers of the State of Mexico (Issste) | Biomedgrid

Background: Diabetes Mellitus (DM2) has increased its incidence worldwide and in Mexico. The prevalence of Gestational Diabetes Mellitus in Mexico ranges from 4 to 14%. The risk of postpartum transformation from DMG to DM2 is 40% and in other studies it is described as a 10-fold risk. There is no work that has characterized clinically, metabolically and hormonally Mexican women who have suffered from GDM, to know the differences that exist with other described populations, establish ethnic risk factors and probable treatment strategies. Material and Methods: A descriptive, cross-sectional study was conducted in 30 Mexican women who during 2018 and 2019 from 18 to 37 years old who were detected during pregnancy with DMG in a Second Level Care Hospital of the ISSSTE, clinical, metabolic characterization was performed and hormonal. Descriptive statistics, correlation of variables with Pearson's P were developed and Odds Ratio was determined for the development of Eclampsia and Preeclampsia. Results: 30 women who suffered from Gestational Diabetes were detected, the age range fluctuated between 18 and 37 years with an average (P) of 28 years and standard deviation (SD) of 6.43. Most women detected had some degree of overweight or obesity, 26 patients (86.6%). Insulin resistance detected in this population in terms of HOMA was established in 16 patients (53.3%). In 5 (16.1%) patients, fasting impaired glucose was determined and in 1 (3.2%) Prediabetes due to glucose> 140 at 2 hrs, as well as in 1 (3.2%) Diabetes Mellitus. Most of the patients had some type of dyslipidemia 28 (93.3%). The average of the group of patients in the case of Gestational Age at the end of pregnancy was 37.7 with a Standard deviation of 1.25, with a range of 36 to 40 weeks gestation, Conclusion: Most of the population of Mexican women who were studied for gestational diabetes had metabolic abnormalities more frequently than those reported in other populations with a similar prevalence of DM2 conversion reported in other ethnic groups