The Evolution of the Nervous System: Invertebrates vs. Vertebrates a useful Instrument and Model to Research New Pharmacological Strategies in some Human Neurodegenerative Conditions | Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.5, No. 5)Publication Date: 2019-10-11
Authors : Mauro Luisetto G Ibrahim Oleg latyschev; Muhammad Akram;
Page : 420-433
Keywords : Nervous Systems; Vertebrates; Invertebrates; Neuroscience; Evolutive; Research; Neurodegenerative; Forensic Sciences; Pharmacology Research; Regenerative Medicine; AJBSR;
Abstract
The nervous system directs and coordinates our movements. It receives stimuli from the environment around us and from all our internal organs. It interprets these stimuli and elaborates responses, which are transmitted to muscles or glands. To compare the nervous systems of invertebrates to vertebrates and between the various vertebrates. Can be a useful instrument in field of neuroscience, molecular biology, forensic science, and pharmacology, regenerative medicine. Why in example some neuronal circuits in superior vertebrates cross themselves like decussatio pyramid or in optical chiasm? And why in brain vs spinal cord grey matter and white matter are inverse (opposite)? And this fact makes possible to verify relationship between degenerative pathology of cortex vs spinal cord under an evolutive approach. And this can be related also to the “brain and spinal cord wasting system” functionality? Is universally known that different neurodegenerative disease involved different CNS parts: cortex (DA), PD (basal nuclei), ALS spinal cord preferentially. And this is an interesting fact: a same organ (CNS) but whit different neuronal sensibility to the damages like neurodegeneration. Is universally known that in superior vertebrates AD is a common disease in animals whit medium -high cognitive functions (frontal cortical and other) and not only a human condition An evolutionary approach makes possible to translate to applied research crucial information to better Explore new therapeutic strategies for some neurodegenerative pathology
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Last modified: 2019-11-19 22:30:27