Nanocarrier Applied in The Distribution of Drugs in the Assistance for the Cancer Treatment | Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.5, No. 6)Publication Date: 2019-10-16
Authors : María Isabel Araya González Lizeth Alejandra Castro Quirós Manuel Jesús Guevara Elizondo Joel Josue Ramírez Alfaro; Jose Vega Baudrit;
Page : 469-480
Keywords : Nanocarriers; Cancer; Drug delivery; Opsonization; Biodistribution; AJBSR;
Abstract
Cancer is the disease that takes more human lives worldwide, currently the treatments available for this disease are very aggressive, among which chemotherapy stands out. As an alternative to these treatments, studies have been carried out for the synthesis of nanocarriers which have as an advantage over conventional treatments, an increase in the solubility of the drug, allow a more specific delivery of this and a lower renal clearance; Among the wide range of materials with which they can be manufactured include dendrines, liposomes and micelles. These manage to be assimilated by the organism through different biological routes distributed either by sustained liberation or response to stimuli. Although the nanocarriers present different challenges, the avenues in the area have allowed them to overcome them in order to be a treatment with smaller cytotoxicity and better efficiency at the preclinical level than conventional treatments
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Last modified: 2019-11-25 14:34:18