COMPARISON BETWEEN EPHEDRINE VERSUS COMBINED PHENYLEPHRINE AND EPHEDRINE FOR HYPOTENSION POST SPINAL IN EMERGENCY CAESARIAN

Introduction: Phenylephrine and ephedrine are drugs that are usually used in hypotension post spinal anesthesia ,in order to improve venous return after sympathetic blockade. The aim of this study was to compare the use of ephedrine versus the combinaison of phenylephrine and ephedrine for in the hypotension post spinal block in emergency caesarian and its effects on the fetus. Methods: This was a Prospective study including 30 patients who underwent an emergency caesarian between August 2019 and October 2019 in Avicenne Maternity hospital. Rabat. Morocco (Maternit? CHU Avicenne Rabat) who were randomized into two groups. One received only ephedrine group E (n=15), and the second received a combinaison of ephedrine and phenylephrine group EP (n=15). The Ephedrine group E received boluses of 5mg of ephedrine, while the combinaison group EP received 50 microgramms + 5 mg of ephedrine. Results: Ephedrine was more effective than phenylephrine combined with ephedrine for hypotension post spinal in emergency caesarian. We noticed lower heart rate with ephedrine combined with phenylephrine. Fetal repercussions such as acidosis were more frequent with the use of Ephedrine. Conclusions: Ephedrine was more effective than phenylephrine combined with ephedrine for hypotension post spinal in emergency caesarian. We noticed lower heart rate with ephedrine combined with phenylephrine. Fetal repercussions such as acidosis were more frequent with the use of ephedrine.