Saccharin as a new organocatalyzed: a fast, highly efficient and environmentally friendly protocol for synthesis of imidazo[1,2-α]pyridine derivatives via a one-three component reaction
Journal: Asian Journal of Green Chemistry (Vol.4, No. 1)Publication Date: 2020-winte
Authors : Sorour Ramezanpour; Zahra Bigdeli; Frank Rominger;
Page : 87-97
Keywords : Three-component reaction Ugi condensation Saccharin Imidazo[1; 2-α]pyridine;
Abstract
In this research article, we report the synthesis of imidazo[1,2-a]pyridine derivatives through Ugi condensation in the presence of saccharin as an organocatalyst used in a three component reaction. The convenient synthetic protocol, short reaction times, easy work up, good to excellent yields and mild reaction conditions make this process both practical and attractive.
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