EFFECT OF ALOIN (ALOEVERA EXTRACT) ON THE LEVELS OF PORPHYROMONAS GINGIVALIS AND AGGREGATIBACTER ACTINOMYCETEMCOMITANS IN CHRONIC GENERALIZED PERIODONTITIS: A CLINICAL & MICROBIOLOGICAL STUDY

Background: Scaling and root planing is the basic treatment modality for periodontal disease. However, mechanical treatment is limited by physical impediments and biochemical considerations. Herbal agents may be used as an adjunct to overcome limitations of mechanical therapy. Thus the aim of this research was to evaluate the effect of Aloin, (aloevera extract) as a local drug delivery (LDD). LDD was used as an adjunct to scaling and root planing (SRP). Study was aimed to compare the clinical and microbiological effect of Aloin on the levels of Porphyromonas gingivalis (P.gingivalis) and Aggregatibacter actinomycetemcomitans (A.A comitans) in the treatment of chronic generalized periodontitis (CGP). Methods: Thirty chronic generalized periodontitis patients with 90 sites were selected including both males and females in the age group of 25?55 years. Three groups were made, 30 sites in each group were assigned. Group A was treated with aloin alone as LDD. Group B was treated with SRP and Aloin, whereas Group C was treated with SRP alone. Plaque sample was collected on baseline, 15th, 30th day for quantitative and qualitative analysis of P.gingivalis and A.A comitans. Results: There was a statistically significant improvement in all clinical and microbiological variables, including plaque and gingival index. However greatest improvement was evident in Group B in terms of reduction in colony forming units(CFU) of P.gingivalis and A.A comitans. Conclusion: Aloin as LDD is a valuable adjunct to SRP in the treatment of chronic generalized periodontitis.