PREVALENCE OF DEPRESSION AMONG PATIENTS WITH VITAMIN D DISTURBANCE AND RESPONSE TO TREATMENT AT ARMED HOSPITALS, TAIF 2018

Objectives: To measure prevalence of depression among vitamin D deficiency and insufficiency patient attending armed hospital, Taif- 2018. Methods: A cross-sectional study was implemented at Alhada Military Hospital, Taif city, Saudi Arabia included all adult patients attending family medicine clinic throughout the period Agust 1st-September 30, 2018 with either newly diagnosed vitamin D deficiency or insufficiency or on regular treatment for vitamin D disturbance. A prepared English interview checklist was used in collecting data from patient. DSM-V criteria were used for diagnosis major depression. Results: The study included 213 patients. Their age ranged between 15 and 88 years, with a mean?SD of 47.6?15.8 years. Majority of the participants had vitamin D insufficiency (81.7%) while only 18.3% of them had vitamin D deficiency. More than one-third of the participants (36.6%) were on current vitamin D treatment whereas 16.5% of them stopped treatment. The duration of vitamin D use was three months or more among 15.5% of the participants. Regarding the current dose, it was 5000 IU/week among 29.1% of the patients. Major depression was diagnosed, based on DSM-V criteria in only two patients (0.9%). Depression was present in 55.5% of the participants, based on PHQ-9 questionnaire; it was mild among 36.6% and moderately severe or severe among 6.5% of them. Vitamin D disturbance was not significantly associated with depression. Conclusions: The rate of depression is high among patients with vitamin D disturbance with no significant difference between patients with vitamin D deficiency and those with insufficiency.