Histochemical Alterations in Bighead Carp (Hypophthalmichthys nobilis Richardson, 1845) Liver Under Two Pesticides Exposure: A Comparative Study

The main aim of the present study was to compare the toxicological effects of a fosetyl-Al and fenamidone based fungicide and a glyphosate based herbicide on the liver lipid accumulation in bighead carp (Hypophthalmichthys nobilis Richardson, 1845) in a short-term laboratory conditions (96 hours). A histochemical method with Sudan III staining was applied. We used 30 mg/L, 38 mg/L and 50 mg/L concentrations fungicide, representing 50, 40, 30 times dilution and 20 mg/L, 40 mg/L and 72 mg/L representing 70, 40, 20 times dilution of the fungicide, respectively. These concentrations were considered as real applicable pesticide concentrations in plant protection practices. Overall, we established a different degree of lipid accumulation in the fish liver. In terms to the histochemical alterations, we found that the fungicide had a more sever effect compared to the herbicide.