Serum renalase and cerebellin levels in acute central serous chorioretinopathy
Journal: EXPERIMENTAL BIOMEDICAL RESEARCH (Vol.3, No. 1)Publication Date: 2020-01-01
Authors : Mete Guler Burak Bilgin Filiz Alkan Baylan Selma Urfalioglu Gamze Gizem Duman;
Page : 1-5
Keywords : Cerebellin; central serous chorioretinopathy; optical coherence tomography; renalase;
Abstract
Aim: To compare the blood renalase and cerebellin-1 levels of acute central serous chorioretinopathy (CSC) patients with healthy subjects. Method: A total of 33 eyes with acute naïve CSC (less than 2 months duration) and 31 healthy subjects were enrolled in this study. Idiopathic CSC was diagnosed based on the presence of a serous detachment of the neurosensory retina involving the macula that was confirmed using optical coherence tomography and leakage at the retinal pigment epithelium level using fluorescein angiography. Blood samples were collected and centrifuged at 4000 g for 10 minutes. The serum samples were collected and stored at -80 °C until required for analysis. Serum renalase and cerebellin-1 levels were measured using an ELISA kit. Results: In CSC group 11 patients were female and 22 patients were male. In control group 10 participants were female and 20 were male. The sex was similar between groups. Mean age in CSC group was 41, 04±5, 94, in control group was 40, 67±6, 53. Mean ages were similar between groups. Mean renalase levels in CSC group was 27, 19±14, 01 ng/ml and in control group was 19, 12±15, 57 ng/mL. Mean renalase level was higher in CSC group. Mean cerebellin levels were 57, 76±29, 72 pg/mL and 52, 50±29, 25 pg/mL in CSC and in control groups, respectively. Mean cerebellin levels were similar in groups. Conclusion: Comparing with healthy subjects serum renalase levels were higher and cerebellin-1 levels were similar in CSC patients.
Other Latest Articles
- Multiple urethroperineal fistula in a boy with posterior urethral valve: A case report of an extremely rare association
- Bilateral single system vaginal ectopic ureters: A rare variant
- Epidermoid inclusion cyst after urethroplasty: A rare complication
- Loop ureterocystoplasty for multiple reimplantation failures of refluxing megaureter to atrophic bladder: A novel technique and its long term outcome
- Extensive chondroid differentiation in a Wilms tumor following chemotherapy: Clinical relevance and implications
Last modified: 2020-01-06 01:17:25