From Lab to Pharmacy Shelves: The Story of a Plant Derived Anticancer Drug, "Paclitaxel"
Journal: Journal of Bioresource Management (JBM) (Vol.2, No. 4)Publication Date: 2015-12-01
Authors : Maira Junjua Department of Biosciences CIIT Islamabad Pakistan Sana Jafar Bioresource Research Centre BRC Islamabad Pakistan Fazeelat Karamat Department of Biosciences CIIT Islamabad Pakistan Faheem Ahmed Department of Biosciences CIIT Islamabad Pakistan;
Page : 28-39
Keywords : secondary metabolites; Taxus brevifolia; taxol; Paclitaxel.;
Abstract
Paclitaxel (Taxol®) is a highly praised anticancer drug, known for its efficiency in treating different cancers. It belongs to a class of compounds called taxanes that are derived from the plants of the genus Taxus. This drug is now FDA approved, but there was a time when the name Taxol was less known to the scientific world. Taxol, being a unique molecule in its structure, properties and mechanism of action, has undergone more than 30 years of trials, and faced a lot of hurdles to leave the bench of a laboratory and reach the shelves of a pharmacy. This review focuses on the story of Taxol, how it began and how it achieved the status of Paclitaxel.
Other Latest Articles
- Anthropogenic Influences on the Tolipir Landscape, Lesser Himalayas, Pakistan
- Status and Future Management of Grey Goral (Naemorhedus goral bedfordi) in Pakistan
- DNA Protective Activity of Peels of Some Vegetables Wastes
- In VitroCulturing and Harvesting of Human Plucked Hair Follicles
- The Distribution, Population Status, and Wildlife Product Trade of Himalayan Musk Deer in Gilgit- Baltistan, Pakistan
Last modified: 2020-01-20 23:40:39