ResearchBib Share Your Research, Maximize Your Social Impacts
Sign for Notice Everyday Sign up >> Login

Periodontal Vaccine-Armour against Periodontitis

Journal: Open Access Journal of Dental Sciences (OAJDS) (Vol.4, No. 4)

Publication Date:

Authors : ;

Page : 1-6

Keywords : Periodontal vaccination; Plantibodies; Synthetic peptides as antigens; Live viral vector vaccines;

Source : Downloadexternal Find it from : Google Scholarexternal

Abstract

The main etiologic factor of periodontitis is oral biofilm comprising of various microorganisms. Studies have shown that there is considerable potential for intervention with the host immune system. Periodontal vaccination is indicated in patients with severe periodontal disease with advanced bone loss. Immunization can be brought about by both whole bacterial cells or one or more of its antigenic components. However, complexity of periodontal pathogenic flora poses a complication in the determination of antigen for the vaccine. Numerous invitro studies and animal studies have proved beyond doubt the efficacy periodontal vaccination. The challenge we face today is the translation of similar results in humans.

Last modified: 2020-01-24 14:14:11