Hereditary Non Polyposis Colon Cancer - A case report
Journal: University Journal of Surgery and Surgical Specialities (Vol.6, No. 1)Publication Date: 2020-02-03
Authors : ASHIQ AHMED A;
Page : 34-36
Keywords : HNPCC; Lynch syndrome; microsatellite instability;
Abstract
A 43 year old male presented with a history of altered bowel habits for 4 months. He was treated elsewhere as a case of amoebiasis. History revealed a strong family history of colorectal malignancies. His father and 3 of his brothers had colonic malignancy. The patient was suspected to have colonic malignancy and evaluated. Hepatic flexure growth was found in CT and confirmed by colonoscopy. A diagnosis of HNPCC was made. The patient was explained of the condition and total procto colectomy was advised. The patient refused radical procedure. Hence segmental resection extended right hemicolectomy was done. Histopathology showed Infiltrating moderately differentiated adenocarcinoma with clear surgical margins. The patient was discharged and started on Chemotherapy. 1 year follow up showed no new lesions. Hereditary nonpolyposis colorectal cancer (HNPCC accounts for about 5-8 of colorectal cancers. Lynch syndrome I is an autosomal dominant inherited disorder characterized by early onset of colorectal cancer, predominance of proximal and multiple tumors, and microsatellite instability. In order to identify HNPCC, the international Amsterdam criteria have been used
Other Latest Articles
- A RARE CASE OF OF GIANT PLEXIFORM NEUROFIBROMA
- Solid Pseudopapillary Tumour of Pancreas - A rare case report
- A case of small bowel GIST mimicking an ovarian mass
- A CASE OF STEROID CELL TUMOR OF OVARY- CASE REPORT AND LITERATURE REVIEW
- A CASE OF CHOLEDOCHAL CYST - ON TABLE SURPRISE AND MANAGEMENT OF POST OPERATIVE COMPLICATION
Last modified: 2020-02-04 14:31:08