ResearchBib Share Your Research, Maximize Your Social Impacts
Sign for Notice Everyday Sign up >> Login

A green synthesis of isoquinolines using Ru(II)/peg-400 as homogeneous recyclable catalyst via C-H/N-N bond activation

Journal: Asian Journal of Green Chemistry (Vol.4, No. 2)

Publication Date:

Authors : ; ; ; ; ;

Page : 159-172

Keywords : Ru(II)/PEG-400; Green synthesis; Homogeneous catalyst; Biodegradable solvent;

Source : Downloadexternal Find it from : Google Scholarexternal

Abstract

A novel and green synthesis of 1-phenyl isoquinoline derivatives has been developed using [Ru(p-cymene)Cl2]2, as a homogeneous recyclable catalyst, with Cu(OAc)2 and AgSbF6 as oxidant and additive respectively, in PEG-400 biodegradable and green solvent via C-H/N-N functionalization of 1-(diphenylmethylene) hydrazine and aryl substituted acetylene. This protocol gives a simple extraction procedure, biodegradable and green solvent, high atom economy, reusable catalytic system and wide substrate scope with high yield of the product for the synthesis of isoquinoline derivatives.

Last modified: 2020-02-08 04:48:53