Performance Metrics of Nanowire Biosensor for Disease Detection

Abstract In this paper, various performance metrics are analysed to check the functionality of Nanowire biosensor. Performance metrics like settling time, sensitivity of the Nanowire biosensor plays a vital role in the disease detection. They are analysed with the help of analyte concentration. The analyte may be either DNA or protein. Sensitivity is mainly responsible for the accurate results in disease detection. This type of biosensor promises the electrical detection of biomolecules with high sensitivity. Here we discuss about the biosensor functionality with respect to the device parameters, physical environment and transient capture of biomolecules. The charged biomolecules detection is taken into account leaving the effect of surface state. This is characterized as the response of the sensor in terms of settling time and sensitivity. Settling time denotes the time taken for stable signal change.With the help of analyte concentration, graph is plotted between setting time and analyte concentration to define the time taken for stable signal change. Sensitivity is obtained by the relative change in sensor characteristics with the binding of target molecules. It is responsible for the attachment of receptor molecules by conducatance modulation through analyte and buffer ion concentration. Keywords: Analyte, Biosensor, Nanowire, Sensitivity