EVALUATION OF URIC ACID LEVELS IN TEARS OF PATIENTS OF VARIOUS GRADES OF MYOPIA

Myopia is major health problem in India. Several studies showed that glaucoma risk increased with more severe myopia. Oxidative damage associated with hypoxia and oxidative stress alter regulatory pathways in myopia. Oxidative stress is caused by an imbalance between the production of reactive oxygen species and ability of the biological systems defense mechanisms necessary to eliminate the stress. Oxidative damage has also been reported to play a role in several ocular diseases including age-related macular degeneration, cataract, uveitis, retinopathy of prematurity, corneal inflammation and keratitis. The antioxidant status of tear fluid is of interest because tears are the first barrier protecting the cornea against light induced oxidative damage and other toxic chemicals. So Uric Acid was measured in tears of patients of myopia (20-40) years and age and sex matched healthy control.