Application of Phylogenetic Analysis in the Study of Mitochondrial Genetic Diseases
Journal: Genetic Disease Study (Vol.2, No. 1)Publication Date: 2018-06-30
Authors : Ertan Kurt Rizal Masdar;
Page : 1-6
Keywords : Mitochondrial; phylogenetic; haplotype; data quality;
Abstract
Mitochondrial genetic diseases are receiving increasing attention. However, the common case-control methods are susceptible to genetic background, population stratification, data quality and other factors that may lead to false positive results. The field of genetic diseases has not been paid enough attention. Therefore, this paper reviews this method and promotes the extensive and in-depth use of mitochondrial genetic diseases.
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