Study on the relationship between chronic tonsillitis and early stage of kidney failure

Objective: to investigate whether chronic tonsillitis is associated with early kidney failure; to analysis the reliability of urine microalbumin as a diagnostic indicator of chronic tonsillitis and early stage of kidney failure; either tonsillectomy is the effective way to prevent complications of chronic tonsillitis and early kidney failure. Methods: 84 patients with chronic tonsillitis who admitted to the department of Otorhinolaryngology, Qinghai University Affiliated Hospital from March 2012 to February 2013 were selected as subjects, 33 males and 51 females who aged between 7-55 years. It was divided into three group according to the course of disease, group A: duration is 1 to 3 years; group B: duration of 3 to 5 years; group C; duration> 5 years; in the immunological laboratory, 12 cases of normal control group were collected, male 7 cases , female 5 cases, aged 7 to 55 years old. The amount of microalbuminuria before and after operation was determined by turbidimetric method. The collected data were analyzed statistically. Results: There was no significant increase in urine microalbumin compared group A and control group, P> 0.05, the difference was not statistically significant. Group B and group C were significantly higher than those in the control group (P <0.05), the difference was statistically significant. The levels of microalbuminuria in group A pre-operation was significantly higher than that of in group C (P <0.05). The difference was statistically significant. The levels of microalbuminuria in group B were significantly higher than those in group C (P <0.05) during preoperation. The difference was statistically significant. The levels of microalbuminuria were significantly decreased in group A post-operation compared to the relatively group pre-operation, P <0.05, the difference was statistically significant. In group B, pre-operative and postoperative comparison, urine microalbumin was significantly decreased, P <0.05, the difference was statistically significant. The levels of microalbuminuria were significantly decreased in post-operative in group C than that of its pre-operation, P <0.05, the difference was statistically significant. Conclusion: Patients with chronic tonsillitis can be complicated by early stage of kidney failure. There is a certain clinical value of urine microalbumin used as a diagnostic indicator of chronic tonsillitis and early kidney failure, and its sensitivity gradually increased with the progress of disease. The only way to prevent the chronic tonsillitis complicated by early kidney failure is to do tonsillectomy.