Bacteriological Analysis of Asymptomatic Bacteriuria in Diabetic Individuals from Rural Area

Abstract: Asymptomatic bacteriuria (ASB) is common in diabetic individuals because of decreased antibacterial activity of the urine as a result of dilution of inhibitory substances.The present study was carried out to find out the causative agents associated with asymptomatic bacteriuria and their antimicrobial susceptibility pattern to institute the rational antibiotic therapy to avoid further morbidity and life threatening complications in diabetic individuals from rural area. A total of 212 urine samples from diabetic individuals and 212 from non-diabetic individuals were processed for identification and antimicrobial susceptibility testing. Of the 212 samples from diabetic individuals,35 (16.50%) were found positive for asymptomatic bacteriuria (ASB) and among the non-diabetic individuals, seven (3.30%) were positive for ASB. In diabetic individuals, E. coli (54.28%) and in non-diabetic individuals, Klebsiella (57.14%) were found to be the most common bacterial isolates. In both the groups imipenem (97.14%) was found to be the most effective antimicrobial agents. It is concluded from the findings that routine screening of asymptomatic bacteriuria in diabetic individuals to initiate rational antibiotic therapy and to avoid further serious complications is of utmost importance.