Recent Thymic Emigrants: A New Method for Thymus Function Evaluation
Journal: AlQalam Journal of Medical and Applied Sciences (Vol.1, No. 1)Publication Date: 2017-01-24
Authors : Eida M. Elmansorry;
Page : 18-24
Keywords : Adenovirus- Hematopoietic stem cell transplantation -Thymus function- Recent Thymic Emigrants - Immune reconstitution;
Abstract
The factors affecting T cells reconstitution post haematopoietic stem cell transplantation (HSCT) are not well characterised. We carried out a prospective analysis of naive T cell reconstitution in 26 HSCT recipients before and during the first six months post transplantation. We analysed the recent thymic emigrants (RTEs) and thereby monitored thymic output and evaluated the thymus function using a new and easy method in comparing to the previous used methods. We found that the thymic-dependent pathway for the T cells reconstitution was activated from the second month in the majority of patients with increasing the numbers of naive T cells. We also compared the RTEs values between the patients with and without adenovirus reactivation, and we found that the patients with adenovirus reactivation had higher numbers of naive T cells on the six month post HSCT.
Other Latest Articles
- In Vitro Anti-MRSA and Antioxidants Activities of Different Aerial Part Extracts of Cakile maritima
- Onset of Action, Clinical Duration, and Recovery Index of Rocuronium: A Comparison with Atracurium
- Screening for Analgesic and Anti-Inflammatory Effect of Antioxidants by Applying Formalin Test Using Albino Mice
- Prevalence of Antibodies Against Chicken Infectious Anaemia Virus Among Free-Range Chickens in Northeastern Libya
- Relevance of Nanomedicine to Veterinary Science: An Insight
Last modified: 2020-05-16 22:51:22