A COMPARATIVE STUDY OF 10% XYLOCAINE SPRAY AND NITROGLYCERINE SPRAY ON CARDIOVASCULAR RESPONSES TO LARYNGOSCOPY AND INTUBATION UNDER GENERAL ANAESTHESIA

The procedure of laryngoscopy and intubation is an integral part of modern-day balanced anaesthesia. It is also the most delicate phase in general anaesthesia. It is performed for most of the major and some minor surgical procedures. The procedure of direct laryngoscopy and intubation is associated with significant hemodynamic changes such as increase in heart rate, arterial pressure and dysrhythmias in up to 90% of the patients. These changes are sometimes fatal if not taken care in time. Various intravenous, sublingual or locally effecting drugs have been used to blunt these adverse effects. Xylocaine 10% spray locally at laryngotracheal mucosa and 0.8mg nitroglycerine intranasal spray is an effective procedure to reduce the exaggerated cardiovascular response. Among these xylocaine is ideal for attenuating the cardiovascular response to laryngoscopy and intubation under general anaesthesia.