SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF NOVEL S-SUBSTITUTED PHENACYL-1, 3, 4-TRIAZOLE-THIOL DERIVATIVES FOR ANTIMICROBIAL STUDIES

In the present study, synthesis and antimicrobial activity of 2,5-disubstituted triazole derivatives 5a-f are described. The structures of the newly synthesized compounds were confirmed by FTIR, 1H NMR, mass and elemental analysis. All compounds were screened for antitubercular and antibacterial activity. The results revealed that most of the compounds showed high or moderate biological activity against tested microorganisms.