Protective Effect of Curcumin Alone and in Combination with Isradipine against Chemicals Induced Seizures and Oxidative Stress in Mice

The isradipine and curcumin have long been used to treat Epilepsy and oxidative stress. In this study the Protective effects of curcumin drugs and antiepileptic activity of isradipine and in combination were examined. The extract of turmeric to reduces the oxidative stress which increased during epileptic seizures and in combination with isradipine which is a calcium channel blocker to treat Seizures. In addition there is effects on increased the time of clonus activity and reduces the oxidative stress were recorded.