Antivirals Effective toward SARS-CoV-2

The review presents the basic data on the chemical compounds manifesting pronounced activity against SARS-CoV-2, the causative agent of the COVID-19 pandemic. The compounds are characterized with their chemical structure, and experimental anti-coronavirus activity in vitro (in cell cultures) and in vivo (in laboratory animals). The existing data on their clinical use in the treatment of patients with COVID-19, double-blind trials included, occupies an important place and are object of discussion on the therapeutic effectiveness of antivirals.