Factors Influencing the Long-Term Prognosis of Autotransplanted Teeth with Complete Root Formation: A Systematic Review

Introduction: Autotransplantation of teeth with complete root formation is indicated for replacement of teeth lost as a result of dental caries, periodontal disease, or trauma in adult patients. The present study aims at assessing the factors influencing long-term prognosis of autotransplanted teeth with complete root formation. Methods: An electronic literature search was conducted in several databases, including PubMed, MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Cochrane Oral Health Group Trials, Register databases from January 1978 through July 2015. Factors potentially contributing to the tooth survival and clinical outcomes were recorded and analyzed. Weighted mean of survival rate and successful rate were also meta-analyzed among selected studies with a follow-up ≥ five years. Results: Seven articles fulfilled the inclusion criteria. Selected studies reported a follow-up period ranging from two months to 11 years, and 5-year survival rates ranging between 76% and 85%. Weighted mean five-year survival rate was 82.1%. Overall, age of the patient, health and types of donor tooth, extraoral storage time, surgeons' experience, root anatomy, health of periodontium, and duration of tooth absence, were decisive factors for the success of the procedure. The mean NOS value was 5.86 ± 0.38, representing an acceptable level of evidence. Conclusion: The current study systematically reviewed the potential factors influencing the long-term prognosis of autotransplanted teeth with complete root formation. The five-year survival rate and success rate of this procedure were 82.1% and 75.6% respectively. Clinicians should take all these factors into consideration when planning an autotransplant procedure.