Effect of Tetracalcium phosphate/Nanomonetite Cement on Dentine Remineralization in Artificial Caries: An In vitro Study

Context: Modern concepts of operative dentistry, popularly known as “minimal intervention dentistry,” propose that only the infected dentin should be removed, leaving the affected dentine that has the potential to remineralize. Aim: The aim of this study was to compare the remineralizing potential of GIC, calcium hydroxide preparations and the novel tetracalcium phosphate/ monetite cement (TTCP/M). Study Design: An experimental in vitro inter group randomized control trial. Materials and Methods: This study consisted of five groups. Group I was a control group-the demineralization of dentin without any remineralization (CGR), Group II was the water suspension of calcium hydroxide sub base (Calxyl) covered with conventional glass ionomer cement (CAG). Group III was light-cured, resin modified calcium ion releasing base liner covered with conventional glass ionomer cement (CLM). Group IV were cavities filled with conventional glass ionomer cement without sub base (GIC) and Group V was the novel tetracalcium phosphate/monetite cement (BPC). Standardized class V cavities were prepared on the buccal and lingual surfaces. Artificial caries like lesions were produced and subsequently restorations of experimental specimens were performed. The depth of demineralization and remineralization were photographed under a polarized light microscope and quantified using a computerized imaging system. Statistical analysis: The obtained results were subjected to statistical analysis using by the Shapiro-Wilk test for normality (P>0.05). Results: Group V, Biphasic porous ceramics (BPC) showed the highest amount of remineralization (20, 65 µm). The expressive, but very thin layer of remineralization there was found in the group II (Water suspension of calcium hydroxide sub base-11, 51 µm). Group IV light-cured, resin modified calcium ion releasing base liner (CLM) covered with conventional glass ionomer cement there had a less thickness (14, 58 µm) of the remineralization than group III Glass i ionomer cement without any sub base-16, 30 µm, but the density of their mineralisation in this group was more marked.