On the Action of N1, N1-Anhydro-bis(β-hydroxyethyl)-Biguanide Hydrochloride (Abitylguanide, Moroxidine, ABOB) Versus RNA Viruses
Journal: Acta Microbiologica Bulgarica (Vol.32, No. 4)Publication Date: 2016-12-01
Abstract
The review considers the compound N1, N1-anhydro-bis(β-hydroxyethyl)-biguanide hydrochloride (abitylguanide, ABOB) as the first applied in the clinical practice anti-flu drug, which later did not prove efficacious, was officially rejected and classified as an agent whose merit only deserved a place in the history of antivirals. The compound manifested some activity against other RNA-containing viruses (paramyxo) but with contradictory effects, strongly dependent on the test methods used and on the virus inoculation dose (multiplicity of infection).
Other Latest Articles
- Bacterial Contamination of Flower Bee Pollen Production
- Essential Oils of Lavender and Fennel for Inhibiting Tomato Spotted Wilt Virus in Pepper Plants
- Еscherichia coli and Paralytic Shellfish Poisoning Toxins Contamination of Mussels Farmed in Bulgarian Black Sea Coast
- PCR in the Bacterial Vaginosis Diagnostic Algorithm
- Biofilm Subtyping of Stx and 16s rRNA Gene Analysis of Some Bulgarian Shiga Toxin Producing Escherichia coli Isolates
Last modified: 2020-08-01 05:46:28