TO DETERMINE THE EFFICACY OF TOPICAL TREATMENT WITH 1% PROPRANOLOL FOR INFANTILE HEMANGIOMA

Objective: To determine the efficacy of topical treatment with 1% propranolol in the infants with hemangioma. Methodology:This was a prospective study conducted from August 2018 till December 2019 through non-probability convenient sampling technique. Study comprised of 27 infants from the Dermatology Department of Dow University Hospital, Karachi. Infants having hemangioma in any part of body except near orifical opening were included in the study. 1% topical propranolol was applied twice daily to the lesion and any change is size, colour , discharge before and after treatment was noted at each follow up till 3 months.Resolution was recorded at each follow up. Data was analysed in SPSS version 20.0. P-value ≤0.05 was taken as significant. Results: From the total of 27 infants enrolled in the study, 09 (33.3%) were male and 18 were female (66.7%). After treatment, 26 (96.3%) hemangiomas had shrunken. 14 (51.9%) of patients parents termed it as a very good response to treatment and 07 (25.9%) felt complete satisfaction to treatment. On first follow up, only 01 (3.7%) had complete resolution, 04 (14.8%) on second follow up and 06 (22.2%) on third follow up. Conclusion: The present study concluded that 1% topical propranolol was effective as well as safe and convenient to apply for treating infantile hemangiomas.