Diagnosis Guidelines for Screening Celiac Disease – A Systematic Review

Celiac disease (CD) is an autoimmune disorder that is expressed by chronic food sensitivity to gluten. Among the autoimmune diseases, CD is the one that has more expression, having the numbers of new cases increased steadily during the last years. In addition to the most common symptoms, such as low weight, diarrhea and abdominal pain, atypical cases, such as overweight, arise which imply the development of new approaches and diagnostic methodologies. The most obvious diagnosis involves endoscopy, an invasive and costly method that causes discomfort to the patient and overload of the health systems. The protocol methodology for CD diagnosis from WGO, NASPGHAN, ESPGHAN and BSPGHAN, the worldwide most recognized specialist ‘organizations, was analyzed in order to assess if social implications were considered on their guidelines. After a detailed review of the literature, a global chart was completed in order to summarize the most referenced protocols for the screening and CD diagnosis.