Program ACTIVE II: Design and Methods for a Multi-Center Community-Based Depression Treatment for Rural and Urban Adults with Type 2 Diabetes
Journal: Journal of Diabetes Research and Therapy (Vol.1, No. 2)Publication Date: 2015-08-03
Authors : Mary de Groot Jay Shubrook Frank Schwartz W. Guyton Hornsby Jr Yegan Pillay Chandan Saha;
Page : 1-7
Keywords : ;
- Program ACTIVE II: Design and Methods for a Multi-Center Community-Based Depression Treatment for Rural and Urban Adults with Type 2 Diabetes
- Effects of Pedometer Based Walking Program on Diabetes Treatment Satisfaction Scores in Patients with Type 2 Diabetes Mellitus
- A COMMUNITY BASED CROSS-SECTIONAL STUDY: INCREASING PREVALENCE OF TYPE 2 DIABETES AMONG RURAL ADULT POPULATION OF KARNATAKA, INDIA
- The Influence of Diabetes Self Management Education (DSME) on Self Care Behavior in Type II Diabetes Mellitus Patients in the Working Area of the Sungai Raya Dalam Community Health Center
- Community based cross sectional study on prevalence of risk factors of type 2 Diabetes Mellitus in adult population residing in urban area of Shahjahanpur, Uttar Pradesh
Abstract
Objective: Depression affects one in four adults with type 2 diabetes (T2DM) and is associated with worsened diabetes complications, increased health care costs and early mortality. Rural and low-income urban areas, including the Appalachian region, represent an epicenter of the T2DM epidemic. Program ACTIVE II is a comparative effectiveness treatment trial designed to test whether a combination of cognitive behavioral therapy (CBT) and community-based exercise (EXER) will offer greater improvements in diabetes and depression outcomes compared to individual treatment approaches and usual care (UC). The secondary aims are to assess changes in cardiovascular risk factors across groups and to conduct a costeffectiveness analysis of predicted incidence of cardiovascular complications across groups. Methods: The study is a 2-by-2 factorial randomized controlled trial consisting of 4 treatment groups: CBT alone, EXER alone, combination of CBT and EXER, and UC. Adults with T2DM for > 1 year and who meet DSM-IVTR criteria for Major Depressive Disorder (MDD) are eligible to participate at two rural Appalachian sites (southeastern Ohio and West Virginia) and one urban site (Indianapolis). This type II behavioral translation study uses a community-engaged research (CEnR) approach by incorporating community fitness centers and mental health practices as interventionists. Conclusions: This is the first study to evaluate the comparative effectiveness of combined CBT and exercise in the treatment of depression using community-based intervention delivery. This approach may serve as a national model for expanding depression treatment for patients with T2DM.
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