Long-Term Chronic Diabetes Complications: the Cause, Cure and Prevention

Introduction: The flow-chart of diabetes progression, extended by empirical evidence of daily polyuria-induced Vitamin B deficiency in the blood plasma of diabetes patients, has provided a basis for a theory for the development, cure and prevention of long-term chronic diabetes complications. Theory: The deficiency of Vitamins B1 and B3 causes vasoconstriction which impacts adversely on the exchange of nutrients, gases and particles between blood and tissue, resulting in tissue damage. With time, the accumulated tissue damage manifests as organ dysfunction-diabetes complications. Hypothesis: Vitamin B supplementation to ensure full 24-hour vasodilatation in the microcirculation will stop tissue damage and allow cures of manifested symptoms, naturally. Method: In on-going Open Trial beginning in 2008, tablets containing Vitamin B {nicotinamide (15.0 mg); thiamine hydrochloride (12.5 mg); and Calcium-dpanthothenate (11.0 mg)}, were ingested by patients with suspected diabetes complications in single/multiple organs. Results: Over 200 cures reported included early-stage symptoms of complications in: the eye (retinopathy); kidney (swollen feet/ankles); skin sores (leg, gum, toe back, and head) and restored erectile functions. As prophylactic, the tablets have prevented manifestation of symptoms of complications for over 8 years. The new theory also explains the reported cures of diabetes complications accomplished with high doses of benfotiamine and thiamine. Conclusion: So-called diabetes complications, like scurvy, are not a disease but manifestation of the effects of vitamin deficiency and are curable and preventable.