Effect of Mn(II), Co(II), Ni(II), Cu(II), Zn(II) and Fe(III) Mixed Ligand Complexes on some Bacteria Causing Eyes Infections (BCEI)

The Mn(II), Co(II), Ni(II), Cu(II), Zn(II) and Fe(III) mixed ligand complexes were prepared by using 1,2-dihydroxybenzene (Catechol) as main ligand (HL1) and 2-hydroxybenzaldehyde (Salicyladehyde) as secondary-ligand (HL2). All the prepared mixed ligand complexes were characterized by using several physiochemical tools. Both electronic spectra and magnetic moment measurements exhibited the existence of an octahedral structure for Mn(II), Co(II) and Fe(III) complexes, square planar geometry for Ni(II) and Cu(II) complexes and tetrahedral structure for Zn(II) complex. The effect of the free ligands, metal salts and their mixed ligand complexes were examined on some bacteria species causing eyes infections (BCEI) such as Escherichia coli, Klebsiella pneumouiae and Staphylococcus aureus. Catechol has more effect than salicyldehyde on all tested bacteria, this is due to the existence of phenolic groups which are electron-releasing so increased the activity, meanwhile, the ligand and their mixed ligand complexes exhibited varying degrees of inhibitory effects on the growth of the bacteria strains.