Proliferative verrucous leukoplakia: A case report with Literature Review

Proliferative verrucous leukoplakia (PVL) is a rare and specific disease that differs from oral leukoplakia, which is neither a delimited lesion nor a condition. It is characterized by the appearance in the oral cavity of white plaques in multiple locations and with different forms of presentation (homogeneous, patchy, verrucous) that progress towards oral squamous cell carcinoma in over 70% of all cases. Eventually, PVL tends to become multifocal with a progressive deterioration of the lesions, making it more and more difficult to control. Tobacco use does not seem to have a significant influence on the appearance or progression of PVL. The etiology of the process remains unclear. Here we report a case of proliferative verrucous leukoplakia on left lateral border of tongue in a 35 year old male patient.