Renal Pelvis Squamous Cell Carcinoma with Sarcomatoid Transformation-Review of a Rare Case with Clinical and Pathological Findings

Primary renal pelvis Squamous Cell Carcinoma (SCC) with sarcomatoid transformation is an extremely rare neoplastic entity. The present study reports an unusual case of renal SCC associated with sarcomatoid transformation in an 81-year-old female with a history of nephrolithiasis. Abdominal CT study revealed an 11.6 cm cystic mass in the left kidney. Histopathology and immunohistochemical examination of the radical nephrectomy specimen showed squamous cell carcinoma with sarcomatoid transformation in the renal pelvis. To better understand the disease a systematic literature review was performed.