Evaluating Role of Clinical Pharmacist in Dietary Interventions Among Dyslipidemic Patients: A Prospective Study
Journal: Pakistan Journal of Pharmaceutical Research (Vol.4, No. 2)Publication Date: 2018-07-01
Authors : Aqsa Afzal Syed NisarHussain Shah Muhammad Fawad Rasool Nabeela Ameer;
Page : 73-80
Keywords : Weight; BMI; Total cholesterol; Triglycerides; Low density lipoproteins; High density lipoproteins;
Abstract
Purpose: To investigate the effect of pharmacist dietary interventions on lipid levels of dyslipidemic patients.
Methods: A randomized controlled trial was carried out on 266 dyslipidemic patients being studied period of 6 months in patients of Southern Punjab. Controlled group patients followed the standard medical care by the physician and intervention group followed with interventionary dietary advices by the clinical pharmacist who were based on ATP III Guidelines. Results: The results between the control and intervention groups were compared by using independent t-test and paired t-test using α value of 0.05. Statistically significant reductions in weight (kg) and BMI (kg/m2) were observed in both groups (p value <0.0001) but mean reductions were more in intervention group as compared to the control group (-3.47, -1.74) respectively. Similarly, significant reductions were also observed between patients of both groups in Total Cholesterol (TC), Triglycerides (TG), Low density lipoproteins (LDL) (αvalue <0.0001) but mean reductions were found increased in intervention group in comparison to control group in TC, TG, LDL (-28.77 mg/dL, -33.90 mg/dL, -25.29 mg/dL) respectively. Statistically insignificant difference was observed in High density lipoproteins (HDL) level in both intervention and control group (p-value =0.47, 0.30) respectively but mean value of intervention group increased (0.78 mg/dL) while mean value of control group decreased (-1.19 mg/dL). Slight addition in mean HDL level was noticed in intervention group 2.49 mg/dL (p value <0.0001) as compared to control group. Conclusion: Pharmacist dietary interventions can improve lipid levels of dyslipidemic patients.
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